⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607151 | 1.00 | — | — | |
| SCHEMBL5306179 | 0.80 | CYP2D6 (0.32) | — | |
| SCHEMBL30803975 | 0.80 | CYP2D6 (0.32) | — | |
| SCHEMBL5903240 | 0.80 | ALDH1A1 (0.52) | — | |
| SCHEMBL10836044 | 0.78 | CYP2D6 (0.35) | — | |
| SCHEMBL108460 | 0.76 | — | — | |
| SCHEMBL29512257 | 0.76 | — | — | |
| SCHEMBL230823 | 0.75 | P2RX7 (0.33) | — | |
| SCHEMBL12925942 | 0.75 | MAOA (0.36) | — | |
| SCHEMBL5300518 | 0.75 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165300-A1 | METHOD OF EXTRACTING VOLATILE COMPOUNDS FROM TOBACCO MATERIAL | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2023-06-01 | — | — | US | claimed |
| US-20220117970-A1 | ARYLQUINAZOLINES | MERCK PATENT GMBH (DE) | 2022-04-21 | — | — | US | claimed |
| US-20200187551-A1 | METHOD | SOUZA CRUZ LTDA. (BR) | 2020-06-18 | — | — | US | claimed |
| EP-3614868-A1 | METHOD | British American Tobacco (Investments) Limited (GB) | 2020-03-04 | — | — | EP | claimed |
| WO-2018197879-A1 | METHOD | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2018-11-01 | — | — | WO | claimed |
| EP-4616913-A2 | GCN2 INHIBITORS AND USES THEREOF | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| EP-3746075-B1 | GCN2 INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-118119707-A | Use of inhibitors to increase CRISPR/Cas insertion efficiency | 阿斯利康(瑞典)有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-118005640-A | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-2994467-A1 | ARYLQUINAZOLINES | Merck Patent GmbH (DE) | 2016-03-16 | — | — | EP | disclosed |
| WO-2014183850-A1 | ARYLQUINAZOLINES | MERCK PATENT GMBH (DE) | 2014-11-20 | — | — | WO | disclosed |
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-1200439-A1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | Novuspharma S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009136-A1 | 1,2-DIHYDRO-1-OXO-PYRAZINO[1,2-A]INDOLE DERIVATIVES | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |
| US-5726172-A | BENZOXAZINONE DERIVATIVES; TREATMENT OF PRETERM LABOR, DYSMENORRHEA | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997025992-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-07-24 | — | — | WO | disclosed |