Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015138 | 0.93 | HPGD (0.54) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL5300317 | 0.91 | NR1I2 (0.48) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL5292819 | 0.91 | NR1I2 (0.48) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL5285074 | 0.91 | LMNA (0.53) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL5410518 | 0.90 | NR1I2 (0.61) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL5281201 | 0.88 | KMT2A (0.53) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL5300268 | 0.88 | NR1I2 (0.61) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL5291553 | 0.88 | NR1I2 (0.60) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL2292224 | 0.88 | NR1I2 (0.56) | HPGDNR1I2ALDH1A1LMNAKMT2A | |
| SCHEMBL2299600 | 0.87 | NPC1 (0.48) | NR1I2LMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828144-A2 | INTEGRIN ANTAGONISTS USEFUL AS ANTICANCER AGENTS | OSI Pharmaceuticals, Inc. (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006053342-A2 | INTEGRIN ANTAGONISTS USEFUL AS ANTICANCER AGENTS | OSI PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | WO | claimed |