Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28805745 | 0.97 | CHRM2 (0.66) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL23607918 | 0.90 | KDM4E (0.59) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5303258 | 0.83 | CHRM2 (0.61) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL184560 | 0.82 | HTT (0.59) | ALDH1A1KDM4ELMNARAB9ANPC1 | |
| SCHEMBL10045186 | 0.82 | CHRM2 (0.88) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL417587 | 0.81 | HDAC3 (0.63) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19133494 | 0.80 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10045185 | 0.80 | CHRM2 (0.92) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2553685 | 0.80 | HTT (0.65) | ALDH1A1LMNARAB9ANPC1POLB | |
| SCHEMBL6766499 | 0.80 | SCN8A (0.52) | HDAC3HDAC1HDAC2HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |