Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252218 | 0.82 | CA1 (0.43) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL2087588 | 0.82 | TDP1 (0.52) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL20153688 | 0.80 | MEN1 (0.38) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL15134348 | 0.80 | APLNR (0.42) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL4083189 | 0.80 | APLNR (0.42) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL3177106 | 0.79 | APLNR (0.44) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL11988220 | 0.79 | TDP1 (0.58) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL1620621 | 0.78 | HDAC3 (0.46) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL1515679 | 0.78 | APLNR (0.41) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL12581071 | 0.78 | MEN1 (0.42) | APLNRTDP1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |