Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.43 |
| ▸ | GNA15 | P30679 | 1/20 | 0.37 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.37 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344065 | 0.86 | FFAR1 (0.51) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL3008871 | 0.81 | FFAR1 (0.68) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL203836 | 0.80 | FFAR1 (0.52) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL530135 | 0.79 | FFAR1 (0.60) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL15397927 | 0.75 | FFAR1 (0.59) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL15800611 | 0.75 | FFAR1 (0.55) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL205346 | 0.74 | TTR (0.46) | FFAR1 | |
| SCHEMBL3045244 | 0.71 | FFAR1 (0.47) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL205845 | 0.70 | FFAR1 (0.58) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL205241 | 0.70 | FFAR1 (0.75) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041123-B1 | FUSED CYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2012-02-01 | — | — | EP | disclosed |