⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diaminopyrimidine SCHEMBL6013998 | 1.00 | HSP90AA1 (0.48) | — | |
| Diaminopyrimidine SCHEMBL29389172 | 1.00 | — | — | |
| Diaminopyrimidine SCHEMBL2744765 | 0.97 | — | — | |
| Diaminopyrimidine SCHEMBL793655 | 0.97 | — | — | |
| Diaminopyrimidine SCHEMBL29556978 | 0.97 | — | — | |
| Diaminopyrimidine SCHEMBL793660 | 0.97 | HSP90AA1 (0.46) | — | |
| Diaminopyrimidine SCHEMBL15389244 | 0.97 | — | — | |
| Diaminopyrimidine SCHEMBL19297740 | 0.97 | — | — | |
| Diaminopyrimidine SCHEMBL30978217 | 0.97 | — | — | |
| Diaminopyrimidine SCHEMBL29280600 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15550 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878468-B | Diamino pyrimidine compound containing phenyl nitrogen mustard fragment and preparation method and application thereof | 贵州大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122036715-A | 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof | 盐城工业职业技术学院 | 2026-05-15 | — | — | CN | claimed |
| WO-2026097624-A1 | METHOD FOR PREPARING CHLORINE-RESISTANT NANOFILTRATION MEMBRANE, AND CHLORINE-RESISTANT NANOFILTRATION MEMBRANE PREPARED THEREWITH | 沃顿科技股份有限公司 | 2026-05-15 | — | — | WO | claimed |
| CN-122006472-A | Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method | 沃顿科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12605401-B2 | Polymers, compositions and methods for treating hyperuricemia | WATERSTONE PHARMACEUTICALS (WUHAN) CO., LTD. (CN) | 2026-04-21 | — | — | US | claimed |
| US-12595236-B2 | Pyrimidine-2,4-diamine compound and preparation method and application thereof | ANHUI MEDICAL UNIVERSITY (CN) | 2026-04-07 | — | — | US | claimed |
| US-20260034237-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | GENMAB AS (DK) | 2026-02-05 | — | — | US | claimed |
| US-20260034238-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | GENMAB AS (DK) | 2026-02-05 | — | — | US | claimed |
| US-20260021115-A1 | Synergistic combinations of Spironolactone, Finasteride, Dutasteride, and Minoxidil | MARTINEZ MICHAEL ANTHONY (US) | 2026-01-22 | — | — | US | claimed |
| US-12478638-B2 | Polymers, compositions and methods for treating hyperuricemia | WATERSTONE PHARMACEUTICALS (WUHAN) CO., LTD. (CN) | 2025-11-25 | — | — | US | claimed |
| US-4627872-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | claimed |
| EP-0184752-A2 | 2,4-Diaminopyrimidines | BAYER AG (DE) | 1986-06-18 | — | — | EP | claimed |
| US-4590270-A | 2,4-diamino-[4-piperidinyl]pyrimidines useful as antibacterial agents, antimalarial agents, antitumors agents | HOFFMANN-LA ROCHE INC. (US) | 1986-05-20 | — | — | US | claimed |
| EP-0028316-B1 | PROCESS FOR THE PREPARATION OF 2,4-DIAMINOPYRIMIDINE | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1984-12-27 | — | — | EP | claimed |
| EP-0037501-B1 | PHARMACEUTICAL PREPARATIONS AND MANUFACATURE | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-07-18 | — | — | EP | claimed |
| EP-0032625-A2 | Water-soluble monoazo dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-29 | — | — | EP | claimed |
| EP-0028316-A1 | Process for the preparation of 2,4-diaminopyrimidine | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1981-05-13 | — | — | EP | claimed |
| US-4232023-A | POTENTIATION OF SULFA DRUGS; ANTIBIOTICS | DICK PIERRE R G | 1980-11-04 | — | — | US | claimed |
| US-4143227-A | FROM THE 2,4-DIAMINO-5-OXY OR HALOMETHYL-PYRIMIDINE AND A 1,2-DIALKOXY OR METHYLENEDIOXY-BENZENE IN AN ACID | HOFFMANN-LA ROCHE INC. (US) | 1979-03-06 | — | — | US | claimed |
| US-4115650-A | Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1978-09-19 | — | — | US | claimed |