Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082732 | 0.96 | LMNA (0.63) | LMNASMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL11346904 | 0.89 | LMNA (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL22681066 | 0.88 | LMNA (0.50) | LMNASMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL4919661 | 0.87 | LMNA (0.50) | LMNASMN1; SMN2 | |
| SCHEMBL8492192 | 0.84 | LMNA (0.51) | LMNASMN1; SMN2KMT2AGAAPKM | |
| SCHEMBL8492195 | 0.82 | LMNA (0.53) | LMNASMN1; SMN2 | |
| SCHEMBL22661238 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL8752140 | 0.81 | LMNA (0.67) | LMNASMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL11527929 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL11527932 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332787-B | Preparation method of contrast agent intermediate acetyl iodide | 安庆朗坤药业有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116332787-A | Preparation method of contrast agent intermediate acetyl iodide | 安庆朗坤药业有限公司 | 2023-06-27 | — | — | CN | claimed |
| EP-0105752-B1 | X-RAY CONTRAST AGENTS | NYEGAARD & CO. A/S (NO) | 1986-05-07 | — | — | EP | claimed |
| EP-0105752-A1 | X-ray contrast agents | NYEGAARD & CO. A/S (NO) | 1984-04-18 | — | — | EP | claimed |
| CN-116496171-B | Synthesis of iohexol | 上海慧聚药业有限公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-4452931-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOISOPHTHALIC BISAMIDES | Bracco Imaging SPA (IT) | 2024-10-30 | — | — | EP | disclosed |
| CN-118414325-A | Process for preparing 2,4, 6-triiodo isophthalic acid diamide | 伯拉考成像股份公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-118239857-A | Preparation method of iodixanol impurity I | 浙江海洲制药股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-116332787-B | Preparation method of contrast agent intermediate acetyl iodide | 安庆朗坤药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116332787-B | Preparation method of contrast agent intermediate acetyl iodide | 安庆朗坤药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116496171-A | Synthesis of iohexol | 上海慧聚药业有限公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2023117667-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOISOPHTHALIC BISAMIDES | BRACCO IMAGING SPA (IT) | 2023-06-29 | — | — | WO | disclosed |
| US-4570007-A | 2-Amino-1-(1,2-dioxolan-4-yl)ethanol compounds, their preparation and use | SHERING AKTIENGESELLSCHAFT (DE) | 1986-02-11 | — | — | US | disclosed |
| US-4547357-A | OPACIFIER FOR X-RAY DIAGNOSIS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1985-10-15 | — | — | US | disclosed |
| EP-0108638-A1 | X-ray contrast agents | NYEGAARD & CO. A/S (NO) | 1984-05-16 | — | — | EP | disclosed |
| EP-0105752-A1 | X-ray contrast agents | NYEGAARD & CO. A/S (NO) | 1984-04-18 | — | — | EP | disclosed |
| US-4364921-A | RADIOPACITY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1982-12-21 | — | — | US | disclosed |
| US-4307072-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4250113-A | 5-SUBSTITUTED N-2,4,6-TRIIODO-N,N'-BIS-(2,3-DIHYDROXYPROPYL) ISOPHTHALAMIDE | NYEGAARD & CO. A/S (NO) | 1981-02-10 | — | — | US | disclosed |
| US-4107286-A | Polyiods benzene derivatives and X-ray contrast media containing the same | GUERBET S.A. (FR) | 1978-08-15 | — | — | US | disclosed |