Biphenyl

Biphenyl

SCHEMBL5305201

C(/C=C/c1ccccc1)=C\c1ccccc1.[NaH].[NaH].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.78
ALDH1A1 P00352 2/20 0.56
MAPK1 P28482 2/20 0.56
TRPA1 O75762 1/20 0.56
LMNA P02545 1/20 0.56
ALOX5 P09917 1/20 0.56
HDAC3 O15379 2/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC7 Q8WUI4 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC10 Q969S8 2/20 0.48
HDAC11 Q96DB2 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
HDAC9 Q9UKV0 2/20 0.48
HDAC5 Q9UQL6 2/20 0.48
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL597093 0.97 MAOB (0.82) MAOBALDH1A1MAPK1TRPA1LMNA
Biphenyl SCHEMBL10622472 0.94 MAOB (0.78) MAOBALDH1A1MAPK1TRPA1LMNA
SCHEMBL11777017 0.92 MAOB (0.74) MAOBALDH1A1MAPK1TRPA1LMNA
(Z)-1,2-Diphenylethene SCHEMBL21045987 0.88 MAOB (0.58) MAOBALDH1A1TRPA1CA1MGLL
SCHEMBL23458007 0.88 MAOB (1.00) MAOBALDH1A1MAPK1TRPA1LMNA
SCHEMBL592744 0.88 MAOB (1.00) MAOBALDH1A1MAPK1TRPA1LMNA
Benzene SCHEMBL9803304 0.88 MAOB (1.00) MAOBALDH1A1MAPK1TRPA1LMNA
SCHEMBL5875512 0.88 MAOB (1.00) MAOBALDH1A1MAPK1TRPA1LMNA
SCHEMBL6853572 0.88 MAOB (1.00) MAOBALDH1A1MAPK1TRPA1LMNA
Benzene SCHEMBL135524 0.88 MAOB (1.00) MAOBALDH1A1MAPK1TRPA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111386340-B Detergent compositions comprising polypeptide variants 宝洁公司 2024-05-24 CN disclosed
CN-117683748-A Detergent compositions comprising polypeptide variants 宝洁公司 2024-03-12 CN disclosed
CN-117529329-A Compositions and methods for treating respiratory distress S.I.S舒洛夫创新科学有限公司 2024-02-06 CN disclosed
EP-3740185-B1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID HSNF LTD (GB) 2023-09-20 EP disclosed
US-11648191-B2 Method and composition for colouring an eyebrow comprising an organic acid PERACHTM LIMITED (GB) 2023-05-16 US disclosed
CN-116064474-A Polypeptides 诺维信公司 2023-05-05 CN disclosed
CN-108368154-B Polypeptides 诺维信公司 2023-02-03 CN disclosed
CN-110300572-B Sulfate-free formulations 罗地亚经营管理公司 2023-01-24 CN disclosed
WO-2022256476-A1 ORRIS ROOT EXTRACTS, COMPOSITIONS, AND METHODS FOR SKIN APPLICATIONS ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2022-12-08 WO disclosed
CN-108350441-B Polypeptides 诺维信公司 2022-09-27 CN disclosed
CN-112899086-A Detergent composition 诺维信公司 2021-06-04 CN disclosed
CN-108350400-B Laundry washing method, use of polypeptides and detergent compositions 诺维信公司 2021-03-30 CN disclosed
CN-106164236-B Detergent composition 诺维信公司 2021-02-02 CN disclosed
EP-3740185-A1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID Perachem Limited (GB) 2020-11-25 EP disclosed
US-20200337968-A1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID HSNF LIMITED (GB) 2020-10-29 US disclosed
CN-110785227-A Method for preparing microcapsules 弗门尼舍有限公司 2020-02-11 CN disclosed
WO-2019141959-A1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID PERACHEM LIMITED (GB) 2019-07-25 WO disclosed
US-20140023770-A1 Use Of Defined Cyclohexenones As Agents For The Superadditive Enhancement Of An Olfactory Impression And Fragrance And/Or Flavor Material Composition SYMRISE AG (DE) 2014-01-23 US disclosed
WO-2007017123-A1 FOAMED PREPARATION SCHWAN-STABILO COSMETICS GMBH & CO. KG (DE) 2007-02-15 WO disclosed
US-20070027223-A1 Foamed preparation SCHWAN-STABILO COSMETICS GMBH & CO. KG (DE) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200337968-A1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID CUTA, TYR, CYP2W1 MAOB 45/4885ALDH1A1 745/4885MAPK1 4161/4885
US-11648191-B2 Method and composition for colouring an eyebrow comprising an organic acid CUTA, TYR, CYP2W1 MAOB 45/4885ALDH1A1 745/4885MAPK1 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.