Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 18/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895745 | 1.00 | MAOA (1.00) | MAOACYP3A4CYP2C9CYP2D6MAOB | |
| SCHEMBL4892393 | 0.93 | MAOA (1.00) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4899161 | 0.85 | MAOA (0.78) | MAOACYP3A4CYP2C9CYP2D6MAOB | |
| SCHEMBL4891794 | 0.84 | MAOA (1.00) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4899653 | 0.82 | MAOA (1.00) | MAOACYP3A4CYP2C9CYP2D6MAOB | |
| SCHEMBL4895064 | 0.82 | MAOA (0.82) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4893372 | 0.81 | MAOA (1.00) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4892331 | 0.81 | CYP3A4 (1.00) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4887421 | 0.81 | MAOA (0.87) | MAOACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4895217 | 0.81 | MAOA (0.81) | MAOACYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753754-A1 | 3- '4- {6-SUBSTITUTED ALKANOYL) PYRIDIN-3-YL} -3-PHENYL! -5- (1H-1, 2, 3-TRIAZOL-1-YLMETHYL) -1, 3-OXAZOLIDIN-2-ONES AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005116022-A1 | 3- `4- {6-SUBSTITUTED ALKANOYL) PYRIDIN-3-YL} -3-PHENYL! -5- (1H-1, 2, 3-TRIAZOL-1-YLMETHYL) -1, 3-OXAZOLIDIN-2-ONES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | WO | disclosed |