Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98018 | 0.99 | NPC1 (0.37) | NPC1POLBRAB9AALDH1A1KMT2A | |
| SCHEMBL5305529 | 0.97 | NPC1 (0.36) | NPC1POLBRAB9AALDH1A1KMT2A | |
| SCHEMBL5301145 | 0.89 | CYP11B1 (0.35) | NPC1POLBRAB9AALDH1A1KMT2A | |
| SCHEMBL97263 | 0.83 | CYP11B1 (0.38) | NPC1POLBALDH1A1KMT2APDE4D | |
| SCHEMBL97993 | 0.82 | HCRTR1 (0.34) | POLBALDH1A1MAPTPDE4DHCRTR1 | |
| SCHEMBL97439 | 0.65 | POLB (0.42) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL98120 | 0.65 | CYP11B1 (0.40) | NPC1ALDH1A1KMT2A | |
| SCHEMBL5297293 | 0.64 | BRD4 (0.47) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL97451 | 0.63 | BRD4 (0.35) | POLBPDE4DHCRTR1HCRTR2 | |
| SCHEMBL97250 | 0.63 | BRD4 (0.48) | POLBALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |