Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97250 | 0.99 | BRD4 (0.48) | BRD4MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5297286 | 0.97 | BRD4 (0.46) | BRD4MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5289604 | 0.92 | BRD4 (0.43) | BRD4MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL97131 | 0.84 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AHTTPDE4A | |
| SCHEMBL98450 | 0.83 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2AL3MBTL1POLB | |
| SCHEMBL97451 | 0.81 | BRD4 (0.35) | BRD4L3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL98558 | 0.81 | POLB (0.45) | MEN1KMT2AL3MBTL1HTTPOLB | |
| SCHEMBL96332 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL96096 | 0.78 | FAAH (0.43) | BRD4L3MBTL1PDE3APOLBACHE | |
| SCHEMBL98191 | 0.76 | MTNR1A (0.34) | ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |