Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329176 | 0.91 | DHODH (0.53) | DHODHALDH1A1GAAHCAR2MME | |
| SCHEMBL5307245 | 0.91 | KDM4E (0.52) | KDM4EBDKRB1ALDH1A1GAAMAPK8 | |
| SCHEMBL5370021 | 0.87 | KDM4E (0.47) | KDM4EBDKRB1DHODHALDH1A1GAA | |
| SCHEMBL5306189 | 0.85 | HCAR2 (0.53) | KDM4EBDKRB1ALDH1A1MAPK8MAPK9 | |
| SCHEMBL5297607 | 0.85 | HCAR2 (0.62) | KDM4EBDKRB1ALDH1A1MAPK8MAPK9 | |
| SCHEMBL5061223 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1MAPK8MAPK9MAPK10 | |
| SCHEMBL5301386 | 0.83 | KDM4E (0.50) | KDM4EBDKRB1ALDH1A1MAPK8MAPK9 | |
| SCHEMBL5306769 | 0.83 | HCAR2 (0.54) | KDM4EHCAR2LTB4RHPGD | |
| SCHEMBL5292540 | 0.82 | GAA (0.54) | KDM4EBDKRB1ALDH1A1GAAMAPK8 | |
| SCHEMBL5300553 | 0.82 | KDM4E (0.49) | KDM4EBDKRB1ALDH1A1GAAMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |