Bicarbonate

Bicarbonate

SCHEMBL530641

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nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA4 P22748 5/20 0.39
CA1 P00915 2/20 0.39
FAHD1 Q6P587 1/20 0.39
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.31
LDHA P00338 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL15189590 0.95 CA4 (0.36) CA4CA1FAHD1
Bicarbonate SCHEMBL1679609 0.95 CA4 (0.42) CA4CA1FAHD1LMNAMEN1
Bicarbonate SCHEMBL904703 0.95
Bicarbonate SCHEMBL14243879 0.95 CA4 (0.42) CA4CA1FAHD1LMNAMEN1
Bicarbonate SCHEMBL15513824 0.90 CA4 (0.39) CA4CA1FAHD1LMNAMEN1
Bicarbonate SCHEMBL8054441 0.90 CA4 (0.39) CA4CA1FAHD1LMNAMEN1
Bicarbonate SCHEMBL1003571 0.90 CA4 (0.39) CA4CA1FAHD1LMNAMEN1
Bicarbonate SCHEMBL6536657 0.90 CA4 (0.39) CA4CA1FAHD1LMNAMEN1
Bicarbonate SCHEMBL10995950 0.90 CA4 (0.39) CA4CA1FAHD1LMNAMEN1
Bicarbonate SCHEMBL14563794 0.90 CA4 (0.39) CA4CA1FAHD1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096803-A Method for stabilizing organic materials using a stabilizer mixture 巴斯夫欧洲公司 2023-05-09 CN claimed
EP-3240056-B1 ORGANIC SEMICONDUCTOR LIQUID COMPOSITION AND METHOD OF PRODUCING ORGANIC SEMICONDUCTOR ELEMENT USING SAID COMPOSITION FUJIFILM CORP (JP) 2020-04-22 EP disclosed
EP-2704992-B1 PREPARATION OF LAYERED DOUBLE HYDROXIDES UNIV OXFORD INNOVATION LTD (GB) 2019-03-20 EP disclosed
US-10158088-B2 Organic semiconductor liquid composition, organic semiconductor element, and method for preparing organic semiconductor element FUJIFILM CORPORATION (JP) 2018-12-18 US disclosed
US-10134812-B2 Electronic device, image display device, and sensor to improve charge injection efficiency SONY CORPORATION (JP) 2018-11-20 US disclosed
US-10008671-B2 Organic thin-film transistor and method for manufacturing same FUJIFILM CORPORATION (JP) 2018-06-26 US disclosed
US-9905768-B2 Semiconductor device and insulating layer-forming composition FUJIFILM CORPORATION (JP) 2018-02-27 US disclosed
EP-3240056-A1 ORGANIC SEMICONDUCTOR LIQUID COMPOSITION, ORGANIC SEMICONDUCTOR ELEMENT AND METHOD FOR PRODUCING SAME FUJIFILM Corporation (JP) 2017-11-01 EP disclosed
US-20170309836-A1 ORGANIC SEMICONDUCTOR LIQUID COMPOSITION, ORGANIC SEMICONDUCTOR ELEMENT, AND METHOD FOR PREPARING ORGANIC SEMICONDUCTOR ELEMENT FUJIFILM CORPORATION (JP) 2017-10-26 US disclosed
US-9799832-B2 Organic thin-film transistor and method for manufacturing same FUJIFILM CORPORATION (JP) 2017-10-24 US disclosed
US-8853014-B2 Method of fabricating a thin-film transistor SONY CORPORATION (JP) 2014-10-07 US disclosed
EP-2704992-A1 PREPARATION OF LAYERED DOUBLE HYDROXIDES Isis Innovation Limited (GB) 2014-03-12 EP disclosed
WO-2012150439-A1 PREPARATION OF LAYERED DOUBLE HYDROXIDES ISIS INNOVATION LIMITED (GB) 2012-11-08 WO disclosed
US-20120248633-A1 THIN-FILM DEVICE, METHOD OF MANUFACTURING THE SAME, AND METHOD OF MANUFACTURING IMAGE DISPLAY APPARATUS SONY CORPORATION (JP) 2012-10-04 US disclosed
EP-2506326-A2 Thin-film device, method of manufacturing the same, and method of manufacturing image display apparatus Sony Corporation (JP) 2012-10-03 EP disclosed
US-8104484-B2 Smoking articles and smoking materials BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2012-01-31 US disclosed
EP-1750838-B1 SMOKING ARTICLES INCLUDING GOLD CATALYST BRITISH AMERICAN TOBACCO CO (GB) 2011-04-06 EP disclosed
US-20070215166-A1 Smoking Articles and Smoking Materials BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2007-09-20 US disclosed
EP-1750838-A2 SMOKING ARTICLES INCLUDING GOLD CATALYST British American Tobacco (Investments) Limited (GB) 2007-02-14 EP disclosed
WO-2005118133-A2 SMOKING ARTICLES INCLUDING GOLD CATALYST BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2005-12-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10158088-B2 Organic semiconductor liquid composition, organic semiconductor element, and method for preparing organic semiconductor element SLCO2A1, SLCO4C1, SLCO2B1 CA4 2320/4885CA1 1024/4885FAHD1 4264/4885
US-10008671-B2 Organic thin-film transistor and method for manufacturing same TET1, FTO, TET2 CA4 2555/4885CA1 2345/4885FAHD1 1068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.