SCHEMBL5307494

SCHEMBL5307494

O=C(NC1CC1)c1ccc(N2CCCN(C(=O)c3ccccc3C(F)(F)F)C2)nc1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCD O00767 6/20 0.57
HPGDS O60760 5/20 0.53
KMT2A Q03164 1/20 0.49
SFRP1 Q8N474 1/20 0.44
GBA1 P04062 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5306879 0.88 SCD (0.59) SCDGBA1
SCHEMBL5309644 0.88 SCD (0.63) SCD
SCHEMBL5312052 0.87 SCD (0.59) SCDHPGDS
SCHEMBL5306424 0.86 SCD (0.61) SCD
SCHEMBL5312015 0.86 KMT2A (0.49) HPGDSKMT2A
SCHEMBL5311994 0.86 SCD (0.66) SCD
SCHEMBL5312244 0.86 SCD (0.61) SCD
SCHEMBL5308876 0.85 SCD (0.63) SCDGBA1
SCHEMBL5309961 0.84 SCD (0.61) SCD
SCHEMBL5310959 0.84 SCD (0.64) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007046867-A2 PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2007-04-26 WO disclosed