Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307494 | 0.86 | SCD (0.57) | KMT2AHPGDS | |
| SCHEMBL5311618 | 0.83 | ALDH1A1 (0.57) | HPGDSKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5312018 | 0.80 | TDP1 (0.46) | KMT2AMEN1TDP1HPGDSEPHX2 | |
| SCHEMBL5307017 | 0.80 | MEN1 (0.44) | KMT2AMEN1TDP1HPGDSEPHX2 | |
| SCHEMBL5312488 | 0.75 | SCD (0.47) | HPGDSKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL5359286 | 0.74 | SCD (0.48) | HPGDSKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL5309578 | 0.74 | SCD (0.48) | HPGDSKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL5309644 | 0.74 | SCD (0.63) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL5307018 | 0.74 | MEN1 (0.41) | KMT2AMEN1TDP1HPGDSEPHX2 | |
| SCHEMBL5306879 | 0.73 | SCD (0.59) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |