Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206400 | 0.87 | — | — | |
| SCHEMBL85668 | 0.87 | — | — | |
| SCHEMBL20408205 | 0.85 | GAA (0.56) | SMN1; SMN2HTTLMNAGAACRBN | |
| SCHEMBL23459791 | 0.74 | — | — | |
| SCHEMBL13058104 | 0.69 | GAA (0.48) | SMN1; SMN2HTTLMNAGAACRBN | |
| SCHEMBL9542421 | 0.69 | GAA (0.73) | SMN1; SMN2HTTLMNAGAACRBN | |
| SCHEMBL11557391 | 0.67 | GAA (0.86) | SMN1; SMN2HTTLMNAGAACRBN | |
| SCHEMBL11562571 | 0.67 | GAA (0.86) | SMN1; SMN2HTTLMNAGAACRBN | |
| SCHEMBL11554085 | 0.67 | GAA (0.86) | SMN1; SMN2HTTLMNAGAACRBN | |
| SCHEMBL11581022 | 0.67 | GAA (0.77) | SMN1; SMN2HTTLMNAGAACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866313-A1 | HIV INTEGRASE INHIBITORS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006103399-A1 | HIV INTEGRASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-10-05 | — | — | WO | disclosed |