SCHEMBL85668

SCHEMBL85668

O=C1CCOCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20408205 0.97 GAA (0.56)
SCHEMBL5308290 0.87 SMN1; SMN2 (0.45)
SCHEMBL23459791 0.85
SCHEMBL13058104 0.80 GAA (0.48)
SCHEMBL9542421 0.79 GAA (0.73)
SCHEMBL11581022 0.77 GAA (0.77)
SCHEMBL11562571 0.77 GAA (0.86)
SCHEMBL11554085 0.77 GAA (0.86)
Dioxane SCHEMBL28901631 0.77 OR51E2 (0.75)
SCHEMBL11557391 0.77 GAA (0.86)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551867-B Fused tricyclic compounds, pharmaceutical compositions and uses thereof 劲方医药科技(上海)有限公司 2024-02-20 CN claimed
EP-4295846-A2 HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF Deciphera Pharmaceuticals, LLC (US) 2023-12-27 EP claimed
EP-3966207-B1 PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS LLC (US) 2023-11-01 EP claimed
US-20230101747-A1 CYCLIC COMPOUNDS AND METHODS OF USING SAME SCHRÖDINGER, INC. 2023-03-30 US claimed
US-11530206-B2 Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof DECIPHERA PHARMACEUTICALS, LLC (US) 2022-12-20 US claimed
EP-4069369-A1 CYCLIC COMPOUNDS AND METHODS OF USING SAME Schrödinger, Inc. (US) 2022-10-12 EP claimed
EP-3966206-A1 HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF Deciphera Pharmaceuticals, LLC (US) 2022-03-16 EP claimed
WO-2021113492-A1 CYCLIC COMPOUNDS AND METHODS OF USING SAME SCHRÖDINGER, INC. (US) 2021-06-10 WO claimed
WO-2020231808-A1 HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS, LLC (US) 2020-11-19 WO claimed
EP-1706147-A2 COMBINATION THERAPY WITH 5-HT sb 1A /sb AND 5-HT sb 1B /sb RECEPTOR ANTAGONISTS Recordati Ireland Limited (IE) 2006-10-04 EP claimed
WO-2005070460-A2 COMBINATION THERAPY WITH 5-HT1A AND 5-HT1B RECEPTOR ANTAGONISTS RECORDATI IRELAND LIMITED (IE) 2005-08-04 WO claimed
US-5349045-A Polymer derived from cyclic amide and medical devices manufactured therefrom UNITED STATES SURGICAL CORPORATION (US) 1994-09-20 US claimed
EP-4709712-A1 GSK3A INHIBITORS AND METHODS OF USE THEREOF Blueprint Medicines Corporation (US) 2026-03-18 EP disclosed
EP-4709376-A1 FUSED RING KRAS INHIBITORS FOR TREATING DISEASE Blossomhill Therapeutics, Inc. (US) 2026-03-18 EP disclosed
US-12528828-B2 Substituted pyrido[4,3-d]pyrimidines as KRAS modulators ALTEROME THERAPEUTICS, INC. (US) 2026-01-20 US disclosed
US-20250375432-A1 COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2025-12-11 US disclosed
WO-1996035677-A1 NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES G.D. SEARLE & CO. (US) 1996-11-14 WO disclosed
US-5483009-A Polymer derived from cyclic amide and medical devices manufactured therefrom UNITED STATES SURGICAL CORPORATION (US) 1996-01-09 US disclosed
US-5446108-A Polymer derived from cyclic amide graft copolymer and medical devices manufactured therefrom UNITED STATES SURGICAL CORPORATION (US) 1995-08-29 US disclosed
US-5349045-A Polymer derived from cyclic amide and medical devices manufactured therefrom UNITED STATES SURGICAL CORPORATION (US) 1994-09-20 US disclosed