Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 16/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308119 | 0.93 | CASR (0.48) | CASRDAO | |
| SCHEMBL5313085 | 0.91 | CASR (0.51) | CASR | |
| SCHEMBL5307986 | 0.89 | CASR (0.45) | CASRDAO | |
| SCHEMBL5311949 | 0.88 | CASR (0.47) | CASR | |
| SCHEMBL5310935 | 0.88 | CASR (0.48) | CASRDAOALDH1A1ALDH1A3 | |
| SCHEMBL5311895 | 0.86 | GNRHR (0.42) | CASR | |
| SCHEMBL5311327 | 0.86 | CASR (0.52) | CASRDAOALDH1A1ALDH1A3 | |
| SCHEMBL5308844 | 0.85 | CASR (0.55) | CASR | |
| SCHEMBL5312353 | 0.84 | CASR (0.54) | CASR | |
| SCHEMBL5310106 | 0.84 | CASR (0.41) | CASRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | claimed |
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |