Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846708 | 0.79 | ALOX5 (0.40) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL9091231 | 0.72 | POLB (0.33) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL21669924 | 0.70 | KMT2A (0.40) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL11313257 | 0.70 | KMT2A (0.45) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL9782148 | 0.67 | — | — | |
| SCHEMBL11702005 | 0.67 | — | — | |
| SCHEMBL948260 | 0.67 | — | — | |
| SCHEMBL10806343 | 0.67 | — | — | |
| SCHEMBL23851485 | 0.66 | KMT2A (0.56) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL28233756 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028524-A2 | USE OF A DERIVATIVE OF IMIDAZOLE FOR THE TREATMENT OF LEUKOTRIENE RELATED DISORDERS | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2007-03-15 | — | — | WO | claimed |
| WO-2007028524-A2 | USE OF A DERIVATIVE OF IMIDAZOLE FOR THE TREATMENT OF LEUKOTRIENE RELATED DISORDERS | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2007-03-15 | — | — | WO | disclosed |