Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 17/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 15/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 15/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 15/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 15/20 | 0.54 |
| ▸ | DRD2 | P14416 | 11/20 | 0.54 |
| ▸ | DRD4 | P21917 | 11/20 | 0.54 |
| ▸ | DRD3 | P35462 | 11/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96646 | 0.87 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL98519 | 0.79 | CHRM1 (0.37) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL11070246 | 0.66 | DRD4 (0.55) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL95996 | 0.65 | PIM1 (0.40) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL11064440 | 0.64 | DRD4 (0.55) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL97527 | 0.64 | CHRM2 (0.39) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL11066728 | 0.63 | MEN1 (0.54) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL97445 | 0.63 | POLB (0.43) | — | |
| SCHEMBL6219793 | 0.63 | DRD2 (0.63) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL97439 | 0.63 | POLB (0.42) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |