Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.39 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.39 |
| ▸ | MAP3K2 | Q9Y2U5 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.36 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307184 | 0.98 | SCD (0.51) | SCDDDR1MAPK11MAPK14DDR2 | |
| SCHEMBL5309118 | 0.95 | SCD (0.51) | SCDEGLN1NPC1ALDH1A1LMNA | |
| SCHEMBL5315077 | 0.91 | SCD (0.47) | SCDMAPK11MAPK14EGLN1 | |
| SCHEMBL5312612 | 0.91 | SCD (0.40) | SCDDDR1MAPK11MAPK14DDR2 | |
| SCHEMBL5309158 | 0.90 | SCD (0.52) | SCDTSHRCXCR4 | |
| SCHEMBL5315085 | 0.90 | SCD (0.51) | SCDMAPK14CXCR4 | |
| SCHEMBL5315103 | 0.89 | SCD (0.51) | SCDMAPK14 | |
| SCHEMBL5309661 | 0.89 | SCD (0.53) | SCDEGLN1 | |
| SCHEMBL5309835 | 0.87 | SCD (0.51) | SCDEGLN1 | |
| SCHEMBL5314447 | 0.87 | SCD (0.46) | SCDMAPK11MAPK14EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |