Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.46 |
| ▸ | HPGDS | O60760 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307539 | 0.88 | SCD (0.47) | SCD | |
| SCHEMBL5309118 | 0.88 | SCD (0.51) | SCDEGLN1 | |
| SCHEMBL5315077 | 0.87 | SCD (0.47) | SCDMAPK14MAPK11RORCEGLN1 | |
| SCHEMBL5309062 | 0.87 | SCD (0.51) | SCDMAPK14MAPK11EGLN1 | |
| SCHEMBL5307018 | 0.86 | MEN1 (0.41) | HPGDSKMT2AEGLN1 | |
| SCHEMBL5309661 | 0.86 | SCD (0.53) | SCDEGLN1 | |
| SCHEMBL5307184 | 0.86 | SCD (0.51) | SCDMAPK14MAPK11EGLN1 | |
| SCHEMBL5309835 | 0.86 | SCD (0.51) | SCDEGLN1 | |
| SCHEMBL5309158 | 0.85 | SCD (0.52) | SCD | |
| SCHEMBL5307042 | 0.84 | SCD (0.42) | SCDKMT2APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |