Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.62 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | PREP | P48147 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113540 | 0.87 | MGAM (0.56) | MGAMBCAT1PREPKDRCFTR | |
| SCHEMBL24392693 | 0.84 | HPGDS (0.70) | MGAMBCAT1CFTRHDAC3HDAC1 | |
| SCHEMBL7209315 | 0.84 | MGAM (0.59) | MGAMBCAT1PREPKDRCFTR | |
| SCHEMBL13101453 | 0.83 | MGAM (0.52) | MGAMBCAT1PREPKDRCFTR | |
| SCHEMBL6237473 | 0.81 | MGAM (0.65) | MGAMBCAT1KDRCFTRHDAC3 | |
| SCHEMBL2639342 | 0.81 | PPARD (0.57) | MGAMBCAT1PREPKDRCFTR | |
| SCHEMBL17634217 | 0.81 | PLK1 (0.65) | BCAT1HDAC1HDAC2RAB9AHTR1A | |
| SCHEMBL29222038 | 0.81 | HDAC3 (0.61) | MGAMBCAT1PREPKDRCFTR | |
| SCHEMBL2639346 | 0.81 | MGAM (0.56) | MGAMBCAT1PREPKDRCFTR | |
| SCHEMBL30858823 | 0.81 | HDAC3 (0.61) | MGAMBCAT1PREPKDRCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935221-B1 | QUINOLONE DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2018-02-07 | — | — | EP | disclosed |
| WO-2007038571-A3 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2007-10-11 | — | — | WO | disclosed |
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |