SCHEMBL5309183

SCHEMBL5309183

CC(C)NC(=O)c1ccc(N2CCCN(C(=O)c3cc(F)ccc3C(F)(F)F)C2)nn1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCD O00767 14/20 0.57
DCTPP1 Q9H773 1/20 0.44
HCRTR1 O43613 1/20 0.44
HCRTR2 O43614 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314080 0.87 SCD (0.55) SCDDCTPP1HCRTR1HCRTR2
SCHEMBL5312872 0.85 SCD (0.49) SCDHCRTR1HCRTR2
SCHEMBL5309473 0.81 SCD (0.48) SCDDCTPP1
SCHEMBL936628 0.79 SCD (0.65) SCDDCTPP1
SCHEMBL5310991 0.79 SCD (0.61) SCDDCTPP1
SCHEMBL5307079 0.78 SCD (0.46) SCDHCRTR1HCRTR2
SCHEMBL1378951 0.77 SCD (0.79) SCDDCTPP1
SCHEMBL1380588 0.77 SCD (0.93) SCDDCTPP1
SCHEMBL5309708 0.76 SCD (0.65) SCDDCTPP1
SCHEMBL1380276 0.76 SCD (0.75) SCDDCTPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007046867-A2 PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2007-04-26 WO disclosed