Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | FASN | P49327 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307079 | 0.91 | SCD (0.46) | SCDHCRTR1HCRTR2KDM4EFASN | |
| SCHEMBL5309930 | 0.88 | SCD (0.41) | SCDKDM4EFASNPARP1KCNQ3 | |
| SCHEMBL5309183 | 0.85 | SCD (0.57) | SCDHCRTR1HCRTR2 | |
| SCHEMBL5312271 | 0.85 | KCNQ3 (0.48) | SCDKDM4EFASNPKMRAB9A | |
| SCHEMBL5312874 | 0.83 | SCD (0.42) | SCDHCRTR1HCRTR2KDM4ERAB9A | |
| SCHEMBL5311277 | 0.82 | SCD (0.41) | SCDHCRTR1HCRTR2FASNPOLB | |
| SCHEMBL5306879 | 0.79 | SCD (0.59) | SCDKDM4EPOLB | |
| SCHEMBL5309407 | 0.79 | SCD (0.53) | SCDKDM4EPKMPOLBRAB9A | |
| SCHEMBL2818800 | 0.77 | SCD (0.56) | SCDKDM4EFASNKCNQ3KCNQ2 | |
| SCHEMBL5307094 | 0.77 | SCD (0.60) | SCDKDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |