Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129385 | 1.00 | — | — | |
| SCHEMBL129517 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL129677 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL129797 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL133623 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL129774 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL129760 | 1.00 | — | — | |
| SCHEMBL128642 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL128744 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL95549 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981830-A | PEROXIDES, AZO AND AZIDE COMPOUNDS, FOAMING | JAPAN SYNTHETIC RUBBER CO., LTD. (JA) | 1976-09-21 | — | — | US | claimed |
| EP-1854877-B1 | Process for the deacylation of cyclic lipopeptides | ASTELLAS PHARMA INC (JP) | 2012-02-08 | — | — | EP | disclosed |
| EP-2172546-A1 | Process for the deacylation of cyclic lipopeptides | Astellas Pharma Inc. (JP) | 2010-04-07 | — | — | EP | disclosed |
| EP-0885957-B1 | PROCESS FOR THE DEACYLATION OF CYCLIC LIPOPEPTIDES | ASTELLAS PHARMA INC (JP) | 2009-08-12 | — | — | EP | disclosed |
| EP-1854877-A2 | Process for the deacylation of cyclic lipopeptides | Astellas Pharma Inc. (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-7294449-B1 | Radiation patternable functional materials, methods of their use, and structures formed therefrom | KOVIO, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| EP-1095979-B1 | Olefinic thermoplastic elastomer, composition and use thereof | MITSUI CHEMICALS INC (JP) | 2007-08-29 | — | — | EP | disclosed |
| EP-1666587-A1 | Cyclic lipopeptide acylase | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-6825003-B2 | Cyclic lipopeptide acylase | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-6573084-B1 | Culture of Streptomyces anulatus 4811 (FERM BP-5808); deacylation of the lipid acyl moiety of FR-901379, Echinocandin B, and Aculeacin A | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-5693750-A | MICROBIOCIDAL ACTION AGAINST PNEUMOCYSTIS INFECTIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| US-H1638-H | CYCLIC HEXAPEPTIDE | FURUTA TAKAHISA (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5569646-A | TREATMENT OF PNEUMONIA; MICROBIOCIDES, FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-29 | — | — | US | disclosed |
| EP-0729974-A1 | Cyclic polypeptide with antibiotic activity and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| EP-0644199-A1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5376634-A | Microbiocides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0486011-A2 | Pharmaceutical composition against Pneumocystis carinii | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0462531-A2 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-3987134-A | MANUFACTURE OF FOAMED COMPARTMENTED STRUCTURES | THE FURUKAWA ELECTRIC CO., LTD. (JA) | 1976-10-19 | — | — | US | disclosed |
| US-3981830-A | PEROXIDES, AZO AND AZIDE COMPOUNDS, FOAMING | JAPAN SYNTHETIC RUBBER CO., LTD. (JA) | 1976-09-21 | — | — | US | disclosed |