SCHEMBL133623

SCHEMBL133623

C=CCCCCCCC[O]

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
MAPT P10636 2/20 0.50
ABCC4 O15439 1/20 0.50
ALDH1A1 P00352 4/20 0.43
LMNA P02545 3/20 0.43
LPAR3 Q9UBY5 2/20 0.43
LPAR2 Q9HBW0 1/20 0.43
TRPA1 O75762 3/20 0.41
USP2 O75604 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
HPGD P15428 1/20 0.34
CYP3A4 P08684 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129385 1.00
SCHEMBL129517 1.00 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL129677 1.00 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL129797 1.00 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL129774 1.00 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL530922 1.00 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL129760 1.00
SCHEMBL128642 1.00 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL128744 1.00 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL95549 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5380462-A Cyclohexyl alkenoate compounds HOFFMANN-LA ROCHE INC. (US) 1995-01-10 US claimed
US-20240021012-A1 FINGERPRINT RECOGNITION SENSOR AND OPTICAL ELEMENT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
WO-2022210850-A1 FINGERPRINT AUTHENTICATION SENSOR, AND OPTICAL ELEMENT 富士フイルム株式会社 2022-10-06 WO disclosed
EP-3059235-B1 TETRAZOLINONE DERIVATIVES AND THEIR USE FOR CONTROLLING PESTS SUMITOMO CHEMICAL CO (JP) 2020-10-28 EP disclosed
US-10085450-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-10-02 US disclosed
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-20160270399-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-22 US disclosed
EP-3059235-A1 TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME Sumitomo Chemical Company, Ltd. (JP) 2016-08-24 EP disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
EP-2841433-A1 TETRAZOLINONE COMPOUNDS AND ITS USE Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
EP-0441213-A2 Chiral dioxolanes F. HOFFMANN-LA ROCHE AG (CH) 1991-08-14 EP disclosed
US-5032312-A Liquid crystals HOFFMANN-LA ROCHE INC. (US) 1991-07-16 US disclosed
US-5013476-A Ferroelectric properties, electro-optical indicating device HOFFMANN-LA ROCHE INC. (US) 1991-05-07 US disclosed
EP-0410233-A2 (4-Arylbutyl) cyclohexane derivatives F. HOFFMANN-LA ROCHE AG (CH) 1991-01-30 EP disclosed
EP-0393501-A1 Liquid crystal components with a trans-3-cyclohexylallyloxy group F. HOFFMANN-LA ROCHE AG (CH) 1990-10-24 EP disclosed
US-4925278-A Liquid crystalline esters HOFFMANN-LA ROCHE INC. (US) 1990-05-15 US disclosed
EP-0344557-A2 Liquid crystal components with a trimethylenoxy group F. HOFFMANN-LA ROCHE AG (CH) 1989-12-06 EP disclosed
US-4830470-A Liquid crystalline esters HOFFMANN-LA ROCHE INC. (US) 1989-05-16 US disclosed
EP-0268198-A2 Ferroelectric liquid crystals F. HOFFMANN-LA ROCHE AG (CH) 1988-05-25 EP disclosed
EP-0247466-A2 Liquid-crystal derivatives of phenyl benzoate F. HOFFMANN-LA ROCHE AG (CH) 1987-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10085450-B2 Tetrazolinone compound and use thereof ROS1, TCOF1, RPS20 TSHR 286/4885MAPT 3692/4885ABCC4 384/4885
US-20160270399-A1 TETRAZOLINONE COMPOUND AND USE THEREOF ROS1, TCOF1, RPS20 TSHR 286/4885MAPT 3692/4885ABCC4 384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.