Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312400 | 0.89 | MEN1 (0.48) | EGLN1EGLN3TDP1TOP2A | |
| SCHEMBL5309053 | 0.89 | EGLN1 (0.41) | EGLN1EGLN2EGLN3TOP2A | |
| SCHEMBL5306234 | 0.88 | TDP1 (0.45) | EGLN1EGLN2EGLN3TDP1TOP2A | |
| SCHEMBL5305537 | 0.88 | TDP1 (0.45) | EGLN1TDP1TOP2A | |
| SCHEMBL5309396 | 0.87 | EGLN1 (0.43) | EGLN1EGLN3TDP1TOP2A | |
| SCHEMBL4431453 | 0.87 | EGLN1 (0.53) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL5305557 | 0.83 | HIF1A (0.43) | EGLN1EGLN2EGLN3TDP1TOP2A | |
| SCHEMBL5313516 | 0.83 | EGLN3 (0.43) | EGLN1EGLN3TDP1TOP2A | |
| SCHEMBL5306838 | 0.82 | HIF1A (0.42) | EGLN1EGLN3TDP1TOP2A | |
| SCHEMBL5312020 | 0.82 | HIF1A (0.39) | EGLN1EGLN2EGLN3TDP1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |