Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314669 | 0.91 | BDKRB1 (0.43) | MEN1KMT2AATMKDRDYRK2 | |
| SCHEMBL5310881 | 0.90 | KDR (0.53) | KDRKDM4EGAAMAPTALOX15 | |
| SCHEMBL5312081 | 0.85 | MEN1 (0.41) | MEN1KMT2AATMPRKAA2KDR | |
| SCHEMBL5312929 | 0.83 | KDR (0.42) | PRKAA2KDRDYRK2FAAH | |
| SCHEMBL5312795 | 0.83 | KDR (0.42) | PRKAA2KDRDYRK2FAAH | |
| SCHEMBL5313051 | 0.82 | KDR (0.46) | KDRACHE | |
| SCHEMBL5336891 | 0.82 | KDR (0.55) | KDRACHE | |
| SCHEMBL5313599 | 0.82 | KDR (0.52) | KDRACHE | |
| SCHEMBL5311424 | 0.81 | KDR (0.53) | MEN1KMT2AATMKDRACHE | |
| SCHEMBL5379811 | 0.80 | KDR (0.51) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |