Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314669 | 0.93 | BDKRB1 (0.43) | KDRBDKRB1DYRK2GPR6FAAH | |
| SCHEMBL5312795 | 0.91 | KDR (0.42) | KDRBDKRB1DYRK2FAAHRORC | |
| SCHEMBL5335398 | 0.91 | KDR (0.52) | KDRBDKRB1 | |
| SCHEMBL5312932 | 0.85 | KDR (0.42) | KDRDYRK2CDK6FAAHLTA4H | |
| SCHEMBL5309404 | 0.83 | MEN1 (0.44) | KDRDYRK2FAAHPRKAA2 | |
| SCHEMBL5379811 | 0.83 | KDR (0.51) | KDRBDKRB1 | |
| SCHEMBL5336891 | 0.83 | KDR (0.55) | KDRMAP4K4 | |
| SCHEMBL5311456 | 0.80 | IDO1 (0.44) | BDKRB1DYRK2 | |
| SCHEMBL5312799 | 0.78 | KDR (0.41) | KDRDYRK2CDK6FAAHCDK4 | |
| SCHEMBL5310039 | 0.78 | FAAH (0.39) | DYRK2CDK6FAAHRORCDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |