Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311454 | 0.87 | MEN1 (0.54) | SERPINE1MEN1KMT2ARXFP1KDM4E | |
| SCHEMBL5312360 | 0.85 | GSK3B (0.57) | SERPINE1MEN1KMT2ARXFP1KDM4E | |
| SCHEMBL5309495 | 0.85 | MEN1 (0.52) | SERPINE1MEN1KMT2ARXFP1KDM4E | |
| SCHEMBL5312063 | 0.85 | GSK3B (0.57) | SERPINE1MEN1KMT2ARXFP1KDM4E | |
| SCHEMBL5305369 | 0.85 | KDM4E (0.54) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL821620 | 0.82 | KMT2A (0.76) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL5308223 | 0.78 | MEN1 (0.52) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL5308306 | 0.78 | KDM4E (0.53) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL6046700 | 0.77 | SERPINE1 (0.47) | SERPINE1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL16651672 | 0.76 | MEN1 (0.50) | SERPINE1MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |