Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309416 | 0.86 | MEN1 (0.52) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL5308306 | 0.85 | KDM4E (0.53) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL5304888 | 0.83 | MEN1 (0.56) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL5309948 | 0.82 | MEN1 (0.61) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL15845971 | 0.82 | HIF1A (0.54) | MEN1KMT2ARXFP1KDM4EKDM5A | |
| SCHEMBL821620 | 0.82 | KMT2A (0.76) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL5309020 | 0.81 | SERPINE1 (0.50) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL15846255 | 0.80 | KDM4E (0.51) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL15846617 | 0.80 | KMT2A (0.48) | MEN1KMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL15846825 | 0.80 | THRA (0.48) | MEN1KMT2ARXFP1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |