Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309407 | 0.88 | SCD (0.53) | KDM4EPKMKCNQ3KCNQ2NPC1 | |
| SCHEMBL5312019 | 0.85 | SCD (0.48) | KDM4EPKMNPC1RAB9AMAPT | |
| SCHEMBL5307319 | 0.80 | SCD (0.59) | KCNQ3KCNQ2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5312271 | 0.80 | KCNQ3 (0.48) | KDM4EPKMKCNQ3KCNQ2RAB9A | |
| SCHEMBL5307094 | 0.76 | SCD (0.60) | KDM4ERAB9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL5309112 | 0.74 | SCD (0.53) | KDM4ENPC1RAB9AGAAFASN | |
| SCHEMBL5306879 | 0.74 | SCD (0.59) | KDM4EPOLB | |
| SCHEMBL5307079 | 0.74 | SCD (0.46) | KDM4EPKMKCNQ3KCNQ2RAB9A | |
| SCHEMBL5309076 | 0.74 | SCD (0.43) | KDM4EALDH1A1 | |
| SCHEMBL5309805 | 0.73 | SCD (0.43) | KDM4EPKMKCNQ3KCNQ2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |