Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.48 |
| ▸ | SCD | O00767 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307319 | 0.89 | SCD (0.59) | KCNQ3KCNQ2SCDSMN1; SMN2MAPT | |
| SCHEMBL5309407 | 0.86 | SCD (0.53) | KCNQ3KCNQ2SCDKDM4EPKM | |
| SCHEMBL5307079 | 0.86 | SCD (0.46) | KCNQ3KCNQ2SCDKDM4EPKM | |
| SCHEMBL5312872 | 0.85 | SCD (0.49) | KCNQ3KCNQ2SCDKDM4EPKM | |
| SCHEMBL5313442 | 0.83 | KCNQ3 (0.42) | KCNQ3KCNQ2SCDKDM4EPKM | |
| SCHEMBL5312273 | 0.83 | KCNQ3 (0.44) | KCNQ3KCNQ2SCDKDM4ESMN1; SMN2 | |
| SCHEMBL5315058 | 0.81 | SCD (0.51) | SCD | |
| SCHEMBL5310049 | 0.80 | KDM4E (0.49) | KCNQ3KCNQ2KDM4EPKMSMN1; SMN2 | |
| SCHEMBL5313445 | 0.77 | KCNQ3 (0.43) | KCNQ3KCNQ2SCDSMN1; SMN2MAPT | |
| SCHEMBL5309805 | 0.77 | SCD (0.43) | KCNQ3KCNQ2SCDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |