Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.48 |
| ▸ | GCK | P35557 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313732 | 0.88 | NPC1 (0.46) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5314293 | 0.84 | ADORA2A (0.47) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5311233 | 0.80 | NPC1 (0.51) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5310754 | 0.79 | SCD (0.48) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5313724 | 0.78 | KCNMA1 (0.46) | KCNMA1GCKKMT2AALDH1A1NPC1 | |
| SCHEMBL5309718 | 0.78 | ADORA2A (0.45) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5312258 | 0.76 | SCD (0.47) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5315546 | 0.74 | SCD (0.51) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5313123 | 0.73 | CNR1 (0.45) | ALDH1A1NPC1RAB9A | |
| SCHEMBL5335811 | 0.71 | MEN1 (0.40) | KMT2AALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |