Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391347 | 0.90 | KDM4E (0.55) | KDM4EESR1ESR2TSHRCYP3A4 | |
| SCHEMBL3999898 | 0.88 | KDM4E (0.55) | KDM4ETSHRCYP3A4ALDH1A1NPSR1 | |
| SCHEMBL30842189 | 0.85 | KDM4E (0.55) | KDM4ETSHRALDH1A1HPGDNPSR1 | |
| SCHEMBL3903921 | 0.85 | KDM4E (0.55) | KDM4ETSHRALDH1A1HPGDNPSR1 | |
| SCHEMBL16479493 | 0.81 | ACHE (0.49) | KDM4EESR1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL6615190 | 0.81 | KDM4E (0.54) | KDM4ETSHRCYP3A4ALDH1A1PKM | |
| SCHEMBL31171420 | 0.81 | TSHR (0.60) | KDM4ETSHRCYP3A4ALDH1A1PKM | |
| SCHEMBL31171418 | 0.81 | TSHR (0.60) | KDM4ETSHRCYP3A4ALDH1A1PKM | |
| SCHEMBL28677234 | 0.80 | KDM4E (0.49) | KDM4ETSHRALDH1A1HPGDNPSR1 | |
| SCHEMBL14279020 | 0.80 | TSHR (0.52) | KDM4ETSHRALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |