Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311153 | 0.93 | PTGDR2 (0.61) | PTGDR2AKR1B1 | |
| SCHEMBL5312227 | 0.90 | CCR4 (0.46) | PTGDR2PTGES2CCR4 | |
| SCHEMBL5311159 | 0.87 | PTGDR2 (0.49) | PTGDR2AKR1B1 | |
| SCHEMBL5313725 | 0.82 | KMT2A (0.51) | PTGDR2 | |
| SCHEMBL5310742 | 0.82 | PTGDR2 (0.60) | PTGDR2AKR1B1 | |
| SCHEMBL5313192 | 0.82 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL5313741 | 0.81 | PTGDR2 (0.54) | PTGDR2AKR1B1 | |
| SCHEMBL5311186 | 0.81 | PTGDR2 (0.53) | PTGDR2AKR1B1 | |
| SCHEMBL5313125 | 0.80 | PTGDR2 (0.55) | PTGDR2AKR1B1 | |
| SCHEMBL5313791 | 0.80 | PTGDR2 (0.59) | PTGDR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |