Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312227 | 0.93 | CCR4 (0.46) | PTGDR2MAPTPTGDRSMN1; SMN2HTT | |
| SCHEMBL5311729 | 0.90 | HCRTR1 (0.43) | PTGDR2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5311153 | 0.89 | PTGDR2 (0.61) | PTGDR2FLT1FLT4KDR | |
| SCHEMBL5314252 | 0.86 | PTGDR2 (0.47) | PTGDR2MAPTFLT1FLT4KDR | |
| SCHEMBL5310070 | 0.85 | CA12 (0.43) | PTGDR2MAPTFLT1FLT4KDR | |
| SCHEMBL5312658 | 0.85 | MAPT (0.51) | PTGDR2MAPTFLT1FLT4KDR | |
| SCHEMBL5313784 | 0.84 | USP2 (0.45) | PTGDR2MAPTFLT1FLT4KDR | |
| SCHEMBL5310906 | 0.84 | KMT2A (0.54) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL5310476 | 0.84 | ALDH1A1 (0.46) | PTGDR2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5311262 | 0.83 | PTGDR2 (0.47) | PTGDR2MAPTALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |