Tryptophan

Tryptophan

SCHEMBL531051

CC(C)C[C@H](N)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.82

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.82
MAPT P10636 3/20 0.82
KMT2A Q03164 3/20 0.82
LMNA P02545 2/20 0.82
TSHR P16473 2/20 0.82
BLM P54132 2/20 0.82
PMP22 Q01453 2/20 0.82
MEN1 O00255 2/20 0.82
MPO P05164 1/20 0.82
HIF1A Q16665 1/20 0.82
APAF1 O14727 1/20 0.65
POLB P06746 1/20 0.65
RECQL P46063 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
HTR2A P28223 3/20 0.59
HTR1A P08908 2/20 0.59
HTR2C P28335 2/20 0.59
SLC6A4 P31645 2/20 0.59
HTR7 P34969 2/20 0.59
HTR2B P41595 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL2005670 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL2143522 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28171407 0.95 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28790481 0.95 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL6863186 0.95 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27301798 0.95 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28081358 0.94 KDM4E (0.73) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28831866 0.93 KDM4E (0.71) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL17503874 0.93 KDM4E (0.71) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL29253127 0.93 KDM4E (0.71) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136973-A Multifunctional cyclic peptide and application thereof 山东第二医科大学 2025-06-13 CN claimed
WO-2024181785-A1 SUSTAINED RELEASE PARTICLES CONTAINING OLIGOPEPTIDES AND METHOD FOR PRODUCING SAME 주식회사 포스테라헬스사이언스 2024-09-06 WO claimed
CN-110483618-B Hetero [4] arene derivatives, their preparation and use 青岛科技大学 2022-09-09 CN claimed
US-20220162558-A1 METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CHONDROCYTES BY USING OLIGOPEPTIDES POSTERA HEALTH SCIENCE Inc. (KR) 2022-05-26 US claimed
CN-110483618-A Miscellaneous [4] arene derivatives and its preparation and application UNIV QINGDAO SCIENCE & TECHNOLOGY 2019-11-22 CN claimed
EP-3544992-A1 G-PROTEIN-COUPLED RECEPTOR INTERNAL SENSORS The Regents of The University of California (US) 2019-10-02 EP claimed
WO-2018098262-A1 G-PROTEIN-COUPLED RECEPTOR INTERNAL SENSORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-05-31 WO claimed
US-9164106-B2 Determination of decreased metabolism of tryptophan in diagnosis of autism spectrum disorders GREENWOOD GENETIC CENTER, INC. (US) 2015-10-20 US claimed
US-20130244273-A1 Determination of Decreased Metabolism of Tryptophan in Diagnosis of Autism Spectrum Disorders GREENWOOD GENETIC CENTER, INC. (US) 2013-09-19 US claimed
EP-1642910-B1 Rationally designed antibodies ALEXION PHARMA INC (US) 2012-02-08 EP claimed
US-7482435-B2 Immunoglobulin for use in human therapeutics and diagnostics ALEXION PHARMACEUTICALS, INC. (US) 2009-01-27 US claimed
EP-1589034-B1 Rationally designed antibodies ALEXION PHARMA INC (US) 2008-11-19 EP claimed
EP-1642910-A1 Rationally designed antibodies ALEXION PHARMACEUTICALS, INC. (US) 2006-04-05 EP claimed
EP-1370589-B1 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMA INC (US) 2006-03-15 EP claimed
EP-1589034-A2 Rationally designed antibodies ALEXION PHARMACEUTICALS, INC. (US) 2005-10-26 EP claimed
EP-1370589-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS, INC. (US) 2003-12-17 EP claimed
US-20030049683-A1 Immunoglobulin for use in human therapeutics and diagnostics ALEXION PHARMACEUTICAL, INC. 2003-03-13 US claimed
WO-2002046238-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS, INC. (US) 2002-06-13 WO claimed
EP-4653419-A1 LINKER FOR ANTIBODY-DRUG CONJUGATES, AND ANTIBODY-DRUG CONJUGATE Otsuka Pharmaceutical Co., Ltd. (JP) 2025-11-26 EP disclosed
US-4104123-A GROWTH MEDIUM CONTAINING CERTAIN AMINO ACIDS LES PRODUITS ORGANIQUES DU SANTERRE ORSAN (FR) 1978-08-01 US disclosed