SCHEMBL5310684 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	SCD	O00767	2/20	0.40

▸	TYK2	P29597	3/20	0.38

▸	JAK2	O60674	1/20	0.38

▸	JAK1	P23458	1/20	0.38

▸	JAK3	P52333	1/20	0.38

▸	RORC	P51449	4/20	0.37

▸	CRACR2A	Q9BSW2	1/20	0.35

▸	EGLN1	Q9GZT9	2/20	0.35

▸	GABRA5	P31644	2/20	0.33

▸	MPL	P40238	2/20	0.33

▸	P2RX7	Q99572	2/20	0.33

▸	ITGA4	P13612	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5309303	0.91	SCD (0.44)	SCDRORCCRACR2AEGLN1MPL
SCHEMBL5309835	0.88	SCD (0.51)	SCDEGLN1
SCHEMBL5310683	0.85	SCD (0.42)	SCDTYK2JAK2JAK1JAK3
SCHEMBL5312021	0.82	SCD (0.42)	SCDTYK2JAK2JAK1JAK3
SCHEMBL5309661	0.81	SCD (0.53)	SCDEGLN1
SCHEMBL5309158	0.80	SCD (0.52)	SCD
SCHEMBL5315085	0.79	SCD (0.51)	SCD
SCHEMBL5315103	0.79	SCD (0.51)	SCD
SCHEMBL5309652	0.78	SCD (0.54)	SCDEGLN1
SCHEMBL5307539	0.78	SCD (0.47)	SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007046867-A2	PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS	XENON PHARMACEUTICALS INC. (CA)	2007-04-26	—	—	WO	disclosed