Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | TYK2 | P29597 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309299 | 0.91 | SCD (0.46) | SCDRORCALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL5309833 | 0.87 | SCD (0.53) | SCD | |
| SCHEMBL5310684 | 0.85 | SCD (0.40) | SCDRORCTYK2JAK2JAK1 | |
| SCHEMBL5312019 | 0.82 | SCD (0.48) | SCDALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL5309660 | 0.80 | SCD (0.56) | SCDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5309157 | 0.79 | SCD (0.55) | SCD | |
| SCHEMBL5315083 | 0.78 | SCD (0.54) | SCD | |
| SCHEMBL5315101 | 0.78 | SCD (0.54) | SCD | |
| SCHEMBL5312021 | 0.77 | SCD (0.42) | SCDRORCTYK2JAK2JAK1 | |
| SCHEMBL5309649 | 0.77 | SCD (0.57) | SCDALDH1A1SMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |