Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 7/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310631 | 0.95 | PROKR1 (0.40) | IKBKBCHUKIKBKGSYKATR | |
| SCHEMBL5312760 | 0.92 | PROKR1 (0.37) | SYKPROKR1MAP3K12LCK | |
| SCHEMBL14531392 | 0.90 | PROKR1 (0.40) | SYKPROKR1MAP3K12 | |
| SCHEMBL5417532 | 0.90 | CCNT1 (0.43) | CDK2LCK | |
| SCHEMBL5314910 | 0.89 | PROKR1 (0.39) | SYKPROKR1MAP3K12 | |
| SCHEMBL5312309 | 0.89 | PROKR1 (0.39) | SYKPROKR1MAP3K12 | |
| SCHEMBL5309762 | 0.89 | MKNK2 (0.39) | ATRPROKR1CDK2LCK | |
| SCHEMBL5311872 | 0.89 | CCNT1 (0.44) | CCNA2CDK2LRRK2LCK | |
| SCHEMBL5334096 | 0.87 | HCK (0.38) | SYKPROKR1 | |
| SCHEMBL5312665 | 0.87 | HCK (0.38) | SYKPROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |