Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.37 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.35 |
| ▸ | CDK9 | P50750 | 4/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5417532 | 0.91 | CCNT1 (0.43) | CDK6LCKCCNT1CDK9CDK1 | |
| SCHEMBL5311872 | 0.90 | CCNT1 (0.44) | LCKCCNT1CDK9CDK1CDK2 | |
| SCHEMBL5312760 | 0.89 | PROKR1 (0.37) | LCKPROKR1PAK4 | |
| SCHEMBL5310717 | 0.89 | IKBKB (0.40) | LCKCDK2PROKR1ATR | |
| SCHEMBL5309726 | 0.88 | KDR (0.36) | LCKCCNT1CDK9CDK2 | |
| SCHEMBL5309914 | 0.88 | LCK (0.35) | CDK6NTRK1LCKCCNT1CDK9 | |
| SCHEMBL14531392 | 0.86 | PROKR1 (0.40) | PROKR1 | |
| SCHEMBL5310253 | 0.86 | GPR4 (0.35) | LCKCCNT1CDK9KCNH2 | |
| SCHEMBL5310631 | 0.86 | PROKR1 (0.40) | PROKR1ATR | |
| SCHEMBL5312309 | 0.86 | PROKR1 (0.39) | PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |