SCHEMBL5310757

SCHEMBL5310757

CC(=O)C(C(C)=O)(C(C)=O)C(C)=O.[Zn]

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.39
THPO P40225 1/20 0.39
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
CA1 P00915 2/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
ALDH1A1 P00352 4/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CA2 P00918 1/20 0.31
PTGS1 P23219 1/20 0.31
MMP12 P39900 1/20 0.31
CA4 P22748 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4881380 0.95 LMNA (0.46) LMNATSHRTHPOFFAR3LCK
SCHEMBL9579651 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL5310586 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL30021864 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL15162889 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL23501572 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL8161294 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL38657391 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL4368179 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL29494787 0.91 LMNA (0.42) LMNATSHRTHPOFFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007034997-A2 FLUORESCENT LAMP SHOWA DENKO K.K. (JP) 2007-03-29 WO disclosed