Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310737 | 0.91 | PTGDR2 (0.56) | PTGDR2AKR1B1CYP2C9PTGS1 | |
| SCHEMBL5311148 | 0.84 | PTGDR2 (0.50) | PTGDR2AKR1B1 | |
| SCHEMBL5311186 | 0.79 | PTGDR2 (0.53) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5310742 | 0.73 | PTGDR2 (0.60) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5313791 | 0.71 | PTGDR2 (0.59) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5311153 | 0.71 | PTGDR2 (0.61) | PTGDR2AKR1B1 | |
| SCHEMBL317297 | 0.71 | PTGDR2 (0.63) | PTGDR2AKR1B1CYP2C9PTGS1 | |
| SCHEMBL5313741 | 0.70 | PTGDR2 (0.54) | PTGDR2AKR1B1CYP2C9PTGS1 | |
| SCHEMBL5311647 | 0.70 | PTGDR2 (0.62) | PTGDR2AKR1B1 | |
| SCHEMBL1387138 | 0.70 | PTGDR2 (0.61) | PTGDR2AKR1B1CYP2C9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |