Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523457 | 0.82 | CYP19A1 (0.52) | CYP19A1MEN1LMNASHBGSERPINA6 | |
| SCHEMBL5308814 | 0.79 | CYP19A1 (0.39) | CYP19A1MEN1LMNASHBGSERPINA6 | |
| SCHEMBL5494156 | 0.79 | CYP19A1 (0.35) | CYP19A1MEN1LMNASHBGSERPINA6 | |
| SCHEMBL1418485 | 0.77 | CYP19A1 (0.60) | CYP19A1MEN1LMNASHBGSERPINA6 | |
| SCHEMBL9622002 | 0.76 | OSBP (0.45) | CYP19A1LMNASHBGSERPINA6G6PD | |
| SCHEMBL1419459 | 0.76 | SHBG (0.43) | CYP19A1MEN1LMNASHBGSERPINA6 | |
| SCHEMBL5575291 | 0.75 | SRD5A2 (0.35) | CYP19A1 | |
| SCHEMBL16011818 | 0.75 | MAPT (0.43) | CYP19A1MEN1LMNASHBGSERPINA6 | |
| SCHEMBL16011817 | 0.75 | MAPT (0.43) | CYP19A1MEN1LMNASHBGSERPINA6 | |
| SCHEMBL5308813 | 0.75 | CYP19A1 (0.59) | CYP19A1SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807118-A2 | STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS | Hollis-Eden Pharmaceuticals Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2007030124-A2 | TREATMENT SCREENING METHODS | HOLLIS-EDEN PHARMACEUTICALS, INC (US) | 2007-03-15 | — | — | WO | disclosed |
| WO-2006110172-A2 | STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS | HOLLIS-EDEN PHARMACEUTICALS.INC. (US) | 2006-10-19 | — | — | WO | disclosed |