SCHEMBL5311408

SCHEMBL5311408

NCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ IGF2R P11717 4/20 0.62
▸ GAA P10253 1/20 0.53
▸ LGALS8 O00214 1/20 0.51
▸ LGALS3 P17931 1/20 0.51
▸ LGALS4 P56470 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ TYR P14679 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464373 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL12191970 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL15489111 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL15489112 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL6685329 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL24696627 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL13818478 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL5316339 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL13818477 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL13713744 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10908090-B2 Microarray slides that enhance fluorescent signals via plasmonic interaction Geddes, Chris (US) 2021-02-02 — — US claimed
US-20180045644-A1 MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION Chris Geddes, Director of the Institute of Fluorescence and Professor of Chemistry and 2018-02-15 — — US claimed
EP-3268724-A1 MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION Plasmonix, Inc. (US) 2018-01-17 — — EP claimed
WO-2016148951-A1 MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION PLASMONIX, INC. (US) 2016-09-22 — — WO claimed
CN-109071607-B Vancomycin derivatives, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2022-09-27 — — CN disclosed
CN-113943330-A Sugar-containing structure compound, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2022-01-18 — — CN disclosed
US-10961278-B2 Vancomycin derivative, preparation method, pharmaceutical composition and use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2021-03-30 — — US disclosed
US-10908090-B2 Microarray slides that enhance fluorescent signals via plasmonic interaction Geddes, Chris (US) 2021-02-02 — — US disclosed
US-20190153036-A1 VANCOMYCIN DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2019-05-23 — — US disclosed
CN-109071607-A Vancomycin derivatives, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2018-12-21 — — CN disclosed
US-20180045644-A1 MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION Chris Geddes, Director of the Institute of Fluorescence and Professor of Chemistry and 2018-02-15 — — US disclosed
EP-3268724-A1 MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION Plasmonix, Inc. (US) 2018-01-17 — — EP disclosed
CN-107325159-A One class vancomycin derivatives, its preparation method, pharmaceutical composition and purposes 中国科学院上海药物研究所 2017-11-07 — — CN disclosed
WO-2016148951-A1 MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION PLASMONIX, INC. (US) 2016-09-22 — — WO disclosed
US-20070202014-A1 Tip for biomolecular reaction NISSHINBO INDUSTRIES, INC. (JP) 2007-08-30 — — US disclosed
US-20070154945-A1 Immobilized biomolecule and method of detecting substance capable of interacting with biomolecule NISSHINBO INDUSTRIES, INC. (JP) 2007-07-05 — — US disclosed
EP-1783492-A2 Tip for biomolecular reaction containing an immobilized biomolecule Nisshinbo Industries, Inc. (JP) 2007-05-09 — — EP disclosed
EP-1722228-A1 IMMOBILIZED BIOMOLECULE AND METHOD OF DETECTING SUBSTANCE CAPABLE OF INTERACTING WITH BIOMOLECULE Nisshinbo Industries, Inc. (JP) 2006-11-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961278-B2 Vancomycin derivative, preparation method, pharmaceutical composition and use thereof PEPD, VIP, NRDC IGF2R 3239/4885GAA 309/4885LGALS8 3482/4885
US-20190153036-A1 VANCOMYCIN DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF PEPD, VIP, NRDC IGF2R 3239/4885GAA 309/4885LGALS8 3482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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