SCHEMBL12191970

SCHEMBL12191970

NCCOC1OC(CO)C(O)C(O)C1O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ IGF2R P11717 4/20 0.62
▸ GAA P10253 1/20 0.53
▸ LGALS8 O00214 1/20 0.51
▸ LGALS3 P17931 1/20 0.51
▸ LGALS4 P56470 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ TYR P14679 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464373 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL15489111 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL5311408 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL15489112 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL6685329 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL24696627 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL13818478 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL5316339 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL13818477 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4
SCHEMBL13713744 1.00 IGF2R (0.62) IGF2RGAALGALS8LGALS3LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372395-A1 CAR CELLS TARGETING AN INSERTED LIGAND MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-11-23 — — US disclosed
WO-2023224715-A1 CAR CELLS TARGETING AN INSERTED LIGAND MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-11-23 — — WO disclosed
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2023-10-05 — — US disclosed
US-11766481-B2 Glycan modified short interfering RNA GANNA BIO, INC. (US) 2023-09-26 — — US disclosed
EP-4204441-A1 INSULIN RECEPTOR PARTIAL AGONISTS Merck Sharp & Dohme LLC (US) 2023-07-05 — — EP disclosed
US-20220387607-A1 GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed
US-20220049237-A1 CARRIER FOR ENZYME IMMOBILIZATION USE, AND IMMOBILIZED ENZYME TOKYO INSTITUTE OF TECHNOLOGY (JP) 2022-02-17 — — US disclosed
US-20160303184-A1 VANCOMYCIN-SUGAR CONJUGATES AND USES THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENT RES (JNCASR) (IN) 2016-10-20 — — US disclosed
WO-2015040467-A1 VANCOMYCIN-SUGAR CONJUGATES AND USES THEREOF Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) (IN) 2015-03-26 — — WO disclosed
EP-1200484-B1 METHODS AND REAGENTS MAKING MULTIVALENT ARRAYS AND COMBINATORIAL LIBRARIES OF MULTIVALENT ARRAYS WISCONSIN ALUMNI RES FOUND (US) 2011-10-05 — — EP disclosed
EP-1337229-B1 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES HENKEL AG & CO KGAA (DE) 2009-09-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160303184-A1 VANCOMYCIN-SUGAR CONJUGATES AND USES THEREOF SLC5A2, SLC5A1, SI IGF2R 305/4885GAA 108/4885LGALS8 405/4885
US-11766481-B2 Glycan modified short interfering RNA SNRPE, FUT6, ALG8 IGF2R 112/4885GAA 171/4885LGALS8 65/4885
US-20220387607-A1 GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES NSUN3, RNGTT, SIGLEC7 IGF2R 315/4885GAA 86/4885LGALS8 78/4885
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS INSR, GPR119, IRS1 IGF2R 29/4885GAA 4062/4885LGALS8 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback