Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290491 | 0.95 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL3287489 | 0.79 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL3290102 | 0.78 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL5314021 | 0.77 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL3291496 | 0.77 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL5316197 | 0.77 | P2RX7 (0.60) | P2RX7 | |
| SCHEMBL3288623 | 0.76 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL3290262 | 0.75 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL3292577 | 0.75 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL3288017 | 0.74 | P2RX7 (0.77) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747206-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111003-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |