Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | CDC25B | P30305 | 3/20 | 0.62 |
| ▸ | CDC25A | P30304 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468318 | 0.93 | PBRM1 (0.74) | PBRM1AKR1C3POLBCDC25BCDC25A | |
| SCHEMBL10833340 | 0.88 | PBRM1 (0.62) | PBRM1AKR1C3POLBCDC25BCDC25A | |
| SCHEMBL27339882 | 0.87 | AKR1C3 (0.79) | AKR1C3POLBCDC25BCDC25AHSD17B10 | |
| SCHEMBL17744824 | 0.86 | PBRM1 (0.70) | PBRM1AKR1C3POLBCDC25BCDC25A | |
| SCHEMBL9647460 | 0.84 | PBRM1 (0.68) | PBRM1AKR1C3POLBCDC25BCDC25A | |
| SCHEMBL17744777 | 0.84 | MAPT (0.65) | PBRM1AKR1C3POLBCDC25BCDC25A | |
| SCHEMBL9403450 | 0.84 | MAPT (0.69) | PBRM1AKR1C3POLBHSD17B10ALDH1A1 | |
| SCHEMBL29436991 | 0.84 | MAPT (0.69) | PBRM1AKR1C3POLBHSD17B10ALDH1A1 | |
| SCHEMBL2058538 | 0.83 | AKR1C3 (0.73) | AKR1C3POLBCDC25BCDC25AHSD17B10 | |
| SCHEMBL147608 | 0.83 | PBRM1 (1.00) | PBRM1POLBALDH1A1ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044184-A1 | WATER SOLUBLE PHOTOINITIATOR | ALBEMARLE CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-4058529-A | Polycyclic amino derivatives of pyrrolidone and piperidone | CIBA-GEIGY CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-3919303-A | Manufacture of 3-aminobenzoylbenzoic acids | BASF AG | 1975-11-11 | — | — | US | disclosed |
| US-3919303-A | Manufacture of 3-aminobenzoylbenzoic acids | BASF AG | 1975-11-11 | — | — | US | disclosed |